- 相关推荐
Toposelective synthesis under thermodynamic control and bioactivities of topoisomers based on diethoxycarbonyl glycoluri
Six topoisomers consisting of diethoxycarbonyl glycoluril have been successfully synthesized in one-pot by using a "figure-of-seven" building block through anti-connectivity and syn-connectivity reactions, respectively. The structures of all six topoisomers were first determined by X-ray crystallography. The finding that (±) CT isomers are the dominant products under thermodynamic control can be explained by the calculated relative energies of the six topoisomers. That the (±) CT isomers have the lowest energy is most likely due to the additional intramolecular electrostatic interactions between -NO2 and -OMe groups. The biological activities of the topoisomers were primitively investigated and the results of bioassay showed that the six topoisomers possessed obvious difference of herbicidal activity.
作 者： ZHOU Baohan YIN Guodong WANG Zhiguo CHEN Yunfeng WU Anxin WAN Jian 作者单位： Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, Department of Chemistry, Central China Normal University, Wuhan 430079, China 刊 名： 科学通报（英文版） SCI 英文刊名： CHINESE SCIENCE BULLETIN 年，卷(期)： 2006 51(17) 分类号： O4 关键词： biological activity thermodynamic control topoisomer toposelective synthesis【Toposelective synthesis under thermo】相关文章：
Synthesis and Characterization of Three Diverse Coordination Frameworks under Co-ligand Intervention04-28
Synthesis of p-nitrophenol under normal pressure with A-1 phase transfer catalysis04-28
Synthesis of 4-Aminosalicylglycine04-26
Under Southern Skies：2000悉尼05-04
New Asymmetric Synthesis of Alkannin and Shikonin04-28
第95讲：on a cloud; under a cloud05-04
第183讲：under the gun; gunshy05-04
Synthesis and Antiviral Activities of Chiral Thiourea Derivatives04-29
A Concise and Stereoselective Synthesis of the Cathasterones Side Chain04-27